Dr John Tetteh

Dr John Tetteh has been involved with applied informatics and chemometrics in the analytical sciences for over 15 years. He has both industrial and academic experience in real-world analytical challenges, including characterisation and optimisation of chemical systems, materials and formulations across the pharmaceutical, food, materials, chemical and allied industries.

He also has extensive experience in multivariate data analysis involving computational methods such as artificial neural network/intelligence and multivariate cure resolutions, experimental designs and data engineering.

Dr Tetteh is an experienced software developer who focuses on tools for multivariate analysis and visualisation. His analytical instrumentation expertise includes FTIR, Raman, Mass Spectroscopy, XRD and advance multidimensional chromatographic systems.

Responsibilities within the university

Course co-ordinator

Research and Professional Skills
Data Organisation and Management

Course participation – undergraduate

Intermediate Forensic Science
Multivariate Imaging and Fingerprinting
Further Physical Chemistry
Laboratory Practical
Pharmaceutical Analysis and Testing
Chemometrics

Course participation – postgraduate

Bioinformatics
Multivariate Classifications
Research Methods
Experimental Design and Optimisation
Pharmaceutical Analysis and Testing
Mathematics and Statistics
Pharmaceutical Product Development
Manufacturing and Control

Recently completed PhD programmes supervised

2005: Study of the thermal behaviours of intumescent silicate materials – Ranti Fayokun
2006: A spectroscopic Investigation of the thermal decomposition of cellulose and alginic acid – Steven Coburn
2007: Membrane investigations using Infra-red spectroscopy and multivariate target factor analysis – Wanessa Russeau
2010: Investigation of membrane permeation using ATR-FTIR spectroscopic Imaging and Multivariate target factor analysis – Kerstin T. Mader

Research interests

Current research activities

• Spectroscopic imaging in transdermal drug delivery monitoring and characterisation protocols
• High-throughput experimentation data analysis and management systems
• Applied chemometric systems in food toxin monitoring
• Data management and characterisation of complex GC/LC-MS systems
• Computational methods for analysing complex chemical and biochemical mixture systems.

Publications

Publications, conferences and inventions

Tetteh, J. 2010. Multivariate spectroscopic imaging: an overview and case applications in transdermal drug delivery studies. In: The Royal Society of Chemistry and the Royal Pharmaceutical Society of GB (The Joint Pharmaceutical Analysis Group), Chemometrics and Multivariate Statistics in Pharmaceuticals Development, 22 April 2010.

Tetteh, J. et al. (2010) ATR-FTIR spectroscopy and spectroscopic imaging of solvent and permeant diffusion across model membranes. European Journal of Pharmaceutics and Biopharmaceutics, 74(2), pp. 413–19.

Tetteh, J. et al. (2009) Simultaneous monitoring of drug and solvent diffusion across a model membrane using ATR-FTIR spectroscopy. European Journal of Pharmaceutical Sciences, 38(4,5), pp. 378–83.

Tetteh, J. et al. (2009) Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil® and human skin using ATR-FTIR and multivariate spectral analysis. International Journal of Pharmaceutics, 374(1-2), pp 17–25.

Tetteh, J. et al. (2009) Local examination of skin diffusion using FTIR spectroscopic imaging and multivariate target factor analysis. Analytica Chimica Acta, 642(1-2), pp. 246–56.

Zotor, F.B., Amuna, P., and Tetteh, J. et al. (2009) Age and gender influences on sensory perceptions of novel low cost nutrient-rich food products developed using traditional Ghanaian food. Annals of Nutrition and Metabolism, 54(3), pp. 247–8.

Patent: Apparatus and method for the detection and measurement of Target Compounds such as a food toxin. Inventors: Tetteh, J., Coker, R.D., Andreou, M.P. Patent No. EP2198274 (A1), WO2009047549 (A1), Publication date: 2010-06-23, Applicant: Toximet Ltd. (University of Greenwich Spin Out Company).